論文リスト

当研究所員の行った主な論文発表です。 (最先端研究開発(FIRST)プログラムの成果は左端にFIRSTと記しています)

2017年

Takashi Nishikaze
"Sensitive and Structure-Informative N-Glycosylation Analysis by MALDI-MS; Ionization, Fragmentation, and Derivatization"
Mass Spectrom. (Tokyo) 2017, 6 (1) A0060
西風隆司
"N 結合型糖鎖の負イオン化とフラグメンテーション"
J. Mass Spectrom. Soc. Jpn. 2017, 65 (6) pp 239-244
高橋秀典
"気相ラジカル種を用いた有機分子のフラグメンテーション"
J. Mass Spectrom. Soc. Jpn. 2017, 65 (6) pp 268-273
寺本華奈江
"MALDI-MSによるバクテリア分析"
島津評論, 2017, 74, pp 51-62
Takashi Nishikaze, Hiroki Tsumoto, Sadanori Sekiya, Shinichi Iwamoto, Yuri Miura, Koichi Tanaka
"Differentiation of Sialyl Linkage Isomers by One-Pot Sialic Acid Derivatization for Mass Spectrometry-Based Glycan Profiling"
Anal. Chem. 2017, 89 (4) pp 2353–2360
西風隆司
"脱離イオン化の変遷と生体高分子測定への応用"
J. Mass Spectrom. Soc. Jpn. 2017, 65 (1) pp 7-10

2016年

福山裕子
"液体マトリックスを用いたMALDI-MS分析"
J. Mass Spectrom. Soc. Jpn. 2016, 64 (5) pp 175-178
Yuko Fukuyama, Shunsuke Izumi, Koichi Tanaka
"3-Hydroxy-4-nitrobenzoic Acid as a MALDI Matrix for In-Source Decay"
Anal. Chem. 2016, 88 (16) pp8058-8063
Hidenori Takahashi, Sadanori Sekiya, Takashi Nishikaze, Kei Kodera, Shinichi Iwamoto, Motoi Wada, Koichi Tanaka
"Hydrogen Attachment/Abstraction Dissociation (HAD) of Gas-Phase Peptide Ions for Tandem Mass Spectrometry"
Anal. Chem. 2016, 88 (7) pp 3810-3816
田中耕一
"MSを中心とする分析・医療機器の臨床への貢献"
臨床病理 2016, 64 pp 193-201
Yuko Fukuyama, Chihiro Nakajima, Shunsuke Izumi, Koichi Tanaka
"Membrane Protein Analyses Using Alkylated Trihydroxyacetophenone (ATHAP) as a MALDI Matrix"
Anal. Chem. 2016, 88 (3) pp1688-1695
Nobuko Kawaguchi-Sakita, Kaoru Kaneshiro-Nakagawa, Masahiro Kawashima, Masahiro Sugimoto, Mariko Tokiwa, Eiji Suzuki, Shigeki Kajihara, Yuichiro Fujita, Shinichi Iwamoto, Koichi Tanaka, Masakazu Toi
"Serum immunoglobulin G Fc region N -glycosylation profiling by matrix-assisted laser desorption/ionization mass spectrometry can distinguish breast cancer patients from cancer-free controls"
Biochem. Biophys. Res. Commun. 2016, 469 (4) pp 1140-1145

2015年

Tatsuya Yoshimi, Shinichiro Kawabata, Shu Taira, Alato Okuno, Ryuta Mikawa, Shigeo Murayama, Koichi Tanaka, Osamu Takikawa
"Affinity imaging mass spectrometry (AIMS): high-throughput screening for specific small molecule interactions with frozen tissue sections"
Analyst 2015, 140, pp7202-7208
Sadanori Sekiya, Keishiro Nagoshi, Shinichi Iwamoto, Koichi Tanaka, Mitsuo Takayama
"Timeframe Dependent Fragment Ions Observed in In-Source Decay Experiments with β-Casein Using MALDI MS"
J. Am. Soc. Mass Spectrom. 2015, 26 (9) pp 1588-1598
FIRST Kentaro Morimoto, Takashi Nishikaze, Akiyasu C. Yoshizawa, Shigeki Kajihara, Ken Aoshima, Yoshiya Oda, Koichi Tanaka
"GlycanAnalysis Plug-in: a database search tool for N-glycan structure using mass spectrometry"
Bioinformatics 2015, 31 (13) pp 2217-2219
FIRST Hiroki Kuyama, Akiyasu C. Yoshizawa, Chihiro Nakajima, Mutsumi Hosako, Koichi Tanaka
"Identification of human basic fetoprotein as glucose-6-phosphate isomerase by using N- and C-terminal sequence tags and terminal tag database"
J. Pharm. Biomed. Anal. 2015, 112 (10) pp 116–125
Yuko Fukuyama
"MALDI Matrix Research for Biopolymers"
Mass Spectrom. (Tokyo) 2015, 4 (1) A0037
FIRST Akiyasu C. Yoshizawa, Yuko Fukuyama, Shigeki Kajihara, Hiroki Kuyama, Koichi Tanaka
"Computational Survey of Sequence Specificity for Protein Terminal Tags covering Nine organisms and its Application for Protein Identification"
J. Proteome Res. 2015, 14 (2) pp 756–767

2014年

FIRST 吉沢明康, 田畑剛, 木村剛之, 青島健, 福山裕子, 梶原茂樹, 九山浩樹, 小田吉哉, 田中耕一
"計算プロテオミクス:データベースを利用したタンパク質翻訳後修飾の同定"
新潟医学会雑誌 2014, 128 (10) pp 504-509
FIRST Ken Aoshima, Kentaro Takahashi, Masayuki Ikawa, Takayuki Kimura, Mitsuru Fukuda, Satoshi Tanaka, Howell E Parry, Yuichiro Fujita, Akiyasu C Yoshizawa, Shin-ichi Utsunomiya, Shigeki Kajihara, Koichi Tanaka, Yoshiya Oda
"A simple peak detection and label-free quantitation algorithm for chromatography-mass spectrometry"
BMC Bioinformatics 2014, 15: 376
FIRST Naoki Kaneko, Akinori Nakamura, Yukihiko Washimi, Takashi Kato, Takashi Sakurai, Yutaka Arahata, Masahiko Bundo, Akinori Takeda, Shumpei Niida, Kengo Ito, Kenji Toba, Koichi Tanaka, Katsuhiko Yanagisawa
"Novel plasma biomarker surrogating cerebral amyloid deposition"
Proc. Jpn. Acad., Ser. B 2014, 90, pp 353–364
FIRST Hiroki Kuyama, Chihiro Nakajima, Kaoru Kaneshiro, Chikako Hamana, Kazuya Terasawa, Koichi Tanaka
"Characterization of N-and C-termini of HER2 Protein by mass spectrometry-based sequencing: Observation of two types of N-terminal sequence"
Int. J. Mass Spectrom. 2014, 373, pp 81–87
FIRST Kenji Nakayama, Takahiro Inoue, Sadanori Sekiya, Naoki Terada, Yu Miyazaki, Takayuki Goto, Shigeki Kajihara, Shin-Ichiro Kawabata, Shinichi Iwamoto, Kuniko Ikawa, Junko Oosaga, Hiroaki Tsuji, Koichi Tanaka, Osamu Ogawa
"The C-terminal fragment of prostate-specific antigen, a 2331 Da peptide, as a new urinary pathognomonic biomarker candidate for diagnosing prostate cancer"
PLoS ONE 2014, 9 (9) e107234
FIRST Yuki Ohta, Shinichi Iwamoto, Shin-ichirou Kawabata, Ritsuko Tanimura, Koichi Tanaka
"Salt Tolerance Enhancement of Liquid Chromatography-Matrix-Assisted Laser Desorption/Ionization-Mass Spectrometry Using Matrix Additive Methylenediphosphonic Acid"
Mass Spectrom. (Tokyo) 2014, 3 (1) A0031
FIRST Jingwen Yao, Shin-ichi Utsunomiya, Shigeki Kajihara, Tsuyoshi Tabata, Ken Aoshima, Yoshiya Oda, Koichi Tanaka
"Peptide Peak Detection for Low Resolution MALDI-TOF Mass Spectrometry"
Mass Spectrom. (Tokyo) 2014, 3 (1) A0030
FIRST Shin-ichi Utsunomiya, Yuichiro Fujita, Satoshi Tanaka, Shgeki Kajihara, Ken Aoshima,Yoshiya Oda, Koichi Tanaka
"Signal Processing Algorithm Developments for Mass++ (Ver.2) : Platform Software for Mass Spectrometry"
IPSJ Transactions on Bioinformatics 2014, 7, pp 24-29
FIRST Satoshi Tanaka, Yuichiro Fujita, Howell E. Parry, Akiyasu C. Yoshizawa, Kentaro Morimoto, Masaki Murase, Yoshihiro Yamada, Jingwen Yao, Shin-ichi Utsunomiya, Shigeki Kajihara, Mitsuru Fukuda, Masayuki Ikawa, Tsuyoshi Tabata, Kentaro Takahashi, Ken Aoshima, Yoshito Nihei, Takaaki Nishioka, Yoshiya Oda, Koichi Tanaka
"Mass++: A visualization and analysis tool for mass spectrometry"
J. Proteome Res. 2014, 13 (8) pp 3846–3853
FIRST Takashi Nishikaze, Shin-ichirou Kawabata, Koichi Tanaka
"In-Depth Structural Characterization of N-linked Glycopeptides Using Complete Derivatization for Carboxyl Groups Followed by Positive- and Negative-Ion Tandem Mass Spectrometry"
Anal. Chem. 2014, 86 (11) pp 5360–5369
FIRST Takashi Nishikaze, Shin-ichirou Kawabata, Koichi Tanaka
"Fragmentation Characteristics of Deprotonated N-linked Glycopeptides: Influences of Amino Acid Composition and Sequence"
J. Am. Soc. Mass Spectrom. 2014, 25 (6) pp 988-998
FIRST Naoki Kaneko, Rie Yamamoto, Taka-Aki Sato, Koichi Tanaka
"Identification and quantification of amyloid beta-related peptides in human plasma using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry"
Proc. Jpn. Acad., Ser. B 2014, 90, pp 104-117
FIRST Yusaku Hioki, Ritsuko Tanimura, Shinichi Iwamoto, Koichi Tanaka
"Nano-LC/MALDI-MS Using a Column-Integrated Spotting Probe for Analysis of Complex Biomolecule Samples"
Anal. Chem. 2014, 86 (5) pp 2549–2558
FIRST Yuko Fukuyama, Natsumi Funakoshi, Kohei Takeyama, Yusaku Hioki, Takashi Nishikaze, Kaoru Kaneshiro, Shin-ichirou Kawabata, Shinichi Iwamoto, Koichi Tanaka
"3-Aminoquinoline/p-Coumaric Acid as a MALDI Matrix for Glycopeptides, Carbohydrates, and Phosphopeptides"
Anal. Chem. 2014, 86 (4) pp 1937-1942
FIRST Yuko Fukuyama, Natsumi Funakoshi, Shinichi Iwamoto, Koichi Tanaka
"Adding methanol to α-cyano-4-hydroxycinnamic acid butylamine salt as a liquid matrix to form a homogeneous spot on a focusing plate for highly sensitive and reproducible analyses in matrix-assisted laser desorption/ionization mass spectrometry"
Rapid Commun. Mass Spectrom. 2014, 28, pp 662-664
Mitsuo Takayama, Sadanori Sekiya, Ryunosuke Iimuro, Shinichi Iwamoto, Koichi Tanaka
"Selective and Nonselective Cleavages in Positive and Negative CID of the Fragments Generated from In-Source Decay of Intact Proteins in MALDI-MS"
J. Am. Soc. Mass Spectrom. 2014, 25 (1) pp 120-131

2013年

FIRST Maiko Kusano, Shin-ichirou Kawabata, Yusuke Tamura, Daigou Mizoguchi, Masato Murouchi, Hideya Kawasaki, Ryuichi Arakawa, Koichi Tanaka
"Laser desorption/ionization mass spectrometry (LDI-MS) of lipids with iron oxide nanoparticle-coated targets"
Mass Spectrom. (Tokyo) 2014, 3(1) A0026
FIRST Yusaku Hioki, Hiroki Kuyama, Chikako Hamana, Kohei Takeyama, Koichi Tanaka
"An improved sample preparation method for the sensitive detection of peptides by MALDI-MS"
J. Mass Spectrom. 2013, 48 (11) pp 1217-1223
FIRST Takashi Nishikaze, Shin-ichirou Kawabata, Shinichi Iwamoto, Koichi Tanaka
"Reversible Hydrazide Chemistry-Based Enrichment for O-GlcNAc-Modified Peptides and Glycopeptides Having Non-Reducing GlcNAc Residues"
Analyst 2013, 138 (23) pp 7224-7232
FIRST Yuko Fukuyama, Chihiro Nakajima, Keiko Furuich, Kenichi Taniguchi, Shin-ichirou Kawabata, Shunsuke Izumi, Koichi Tanaka
"Alkylated Trihydroxyacetophenone as a MALDI Matrix for Hydrophobic Peptides"
Anal. Chem. 2013, 85 (20) pp 9444-9448
FIRST Masahiro Kawashima, Noriko Iwamoto, Nobuko Kawaguchi-Sakita, Masahiro Sugimoto, Takayuki Ueno, Yoshiki Mikami, Kazuya Terasawa, Taka-Aki Sato, Koichi Tanaka, Kazuharu Shimizu, Masakazu Toi
"High-Resolution Imaging Mass Spectrometry Reveals Detailed Spatial Distribution of Phosphatidylinositols in Human Breast Cancer"
Cancer Sci. 2013, 10, pp 1372-1379
FIRST Takashi Nishikaze, Shin-ichirou Kawabata, Koichi Tanaka
"Boron forms unexpected glycopeptide derivatives during MALDI-MS experiment"
J. Mass Spectrom. 2013, 48, pp 1005-1009
FIRST Kenichi Taniguchi, Hiroki Kuyama, Shigeki Kajihara, Koichi Tanaka
"MALDI mass spectrometry-based sequence analysis of arginine-containing glycopeptides: improved fragmentation of glycan and peptide chains by modifying arginine residue"
J. Mass Spectrom. 2013, 48, pp 951-960
FIRST Makoto Watanabe, Kazuya Terasawa, Kaoru Kaneshiro, Hiromasa Uchimura, Rie Yamamoto, Yuko Fukuyama, Kazuharu Shimizu, Taka-Aki Sato, Koichi Tanaka
"Improvement of mass spectrometry analysis of glycoproteins by MALDI-MS using 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid"
Anal. Bioanal. Chem. 2013, 405 (12) pp 4289-4293
FIRST Naoki Kaneko, Takayuki Yoshimori, Rie Yamamoto, Daniel J. Capon, Takashi Shimada, Taka-Aki Sato, Koichi Tanaka
"Multi Epitope-Targeting Immunoprecipitation Using F(ab’) Fragments with High Affinity and Specificity for the Enhanced Detection of a Peptide with Matrix-Assisted Laser Desorption Ionization-Time-of-Flight Mass Spectrometry"
Anal. Chem. 2013, 85 (6) pp 3152-3159
嶋田崇史, 九山浩樹, 佐藤孝明, 田中耕一
"MALDI-TOF MSによるシステイン含有ペプチドの検出感度向上を目的とした,ヨードアセチル骨格を有するイオン性マスタグの開発"
島津評論, 2013, 69, pp 223-232
FIRST Makoto Watanabe, Rie Yamamoto, Shinichi Iwamoto, Yuko Fukuyama, Ritsuko Tanimura, Shin-ichirou Kawabata, Taka-Aki Sato, Shunsuke Izumi, Koichi Tanaka
"Potential of radical scavenging reagents as a matrix additive in the direct detection of S-nitrosylated peptides with UV-MALDI MS"
Int. J. Mass Spectrom. 2013, 333, pp 67-71

2012年

Helen Montgomery, Nitin Rustogi, Andreas Hadjisavvas, Koichi Tanaka, Kyriacos Kyriacou, Chris W. Sutton
"Proteomic Profiling of Breast Tissue Collagens and Site-specific Characterization of Hydroxyproline Residues of Collagen Alpha-1-(I)"
J. Proteome Res. 2012, 11 (12) pp 5890−5902
FIRST Takashi Nishikaze, Kaoru Kaneshiro, Shin-ichirou Kawabata, Koichi Tanaka
"Structural Analysis of N-Glycans by the Glycan-Labeling Method Using 3-Aminoquinoline-Based Liquid Matrix in Negative-Ion MALDI-MS"
Anal. Chem. 2012, 84 (21) pp 9453-9461
FIRST Hiroki Kuyama, Chihiro Nakajima, Koichi Tanaka
"Enriching C-terminal peptide from endopeptidase ArgC digest for protein C-terminal analysis"
Bioorg. Med. Chem. Lett. 2012, 22, pp 7163-7168
FIRST Yuko Fukuyama, Kohei Takeyama, Shin-ichirou Kawabata, Shinichi Iwamoto, Koichi Tanaka
"An optimized matrix-assisted laser desorption/ionization sample preparation using a liquid matrix, 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid, for phosphopeptides"
Rapid Commun. Mass Spectrom. 2012, 26, pp 2454-2460
FIRST Kaoru Kaneshiro, Makoto Watanabe, Kazuya Terasawa, Hiromasa Uchimura, Yuko Fukuyama, Shinichi Iwamoto, Taka-Aki Sato, Kazuharu Shimizu, Gozoh Tsujimoto, Koichi Tanaka
"Rapid Quantitative Profiling of N-Glycan by the Glycan-Labeling Method Using 3-Aminoquinoline/α-Cyano-4-hydroxycinnamic Acid"
Anal. Chem. 2012, 84 (16) pp 7146-7151
FIRST Chihiro Nakajima, Hiroki Kuyama, Koichi Tanaka
"Mass spectrometry-based sequencing of protein C-terminal peptide using α-carboxyl group-specific derivatization and COOH capturing"
Anal. Biochem. 2012, 428 (2) pp 167-172
FIRST Takashi Nishikaze, Yuko Fukuyama, Shin-ichirou Kawabata, Koichi Tanaka
"Sensitive Analyses of Neutral N-Glycans using Anion-Doped Liquid Matrix G3CA by Negative-Ion Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry"
Anal. Chem. 2012, 84 (14) pp 6097-6103
FIRST Yuko Fukuyama, Ritsuko Tanimura, Kazuki Maeda, Makoto Watanabe, Shin-Ichirou Kawabata, Shinichi Iwamoto, Shunsuke Izumi, Koichi Tanaka
"Alkylated Dihydroxybenzoic Acid as a MALDI Matrix Additive for Hydrophobic Peptide Analysis"
Anal. Chem. 2012, 84 (9) pp 4237-4243 (Correction; Anal. Chem. 2014, 86 (12) pp 5187-5187)
FIRST Takashi Shimada, Hiroki Kuyama, Taka-Aki Sato, Koichi Tanaka
"Development of iodoacetic acid-based cysteine mass tags: Detection enhancement for cysteine-containing peptide by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry"
Anal. Biochem. 2012, 421 (2) pp 785-787
Sadanori Sekiya, Kenichi Taniguchi, Koichi Tanaka
"On-target separation of analyte with 3-aminoquinoline/-cyano-4-hydroxycinnamic acid liquid matrix for matrix-assisted laser desorption/ionization mass spectrometry"
Rapid Commun. Mass Spectrom. 2012, 26 (6) pp 693-700
Takuya Shuo, Naohiko Koshikawa, Daisuke Hoshino, Tomoko Minegishi, Hiroko Ao-Kondo,Masaaki Oyama, Sadanori Sekiya, Shinichi Iwamoto, Koichi Tanaka, Motoharu Seiki
"Detection of the Heterogeneous O-Glycosylation Profile of MT1-MMP Expressed in Cancer Cells by a Simple MALDI-MS Method"
PLoS ONE 2012, 7 (8) e43751

2011年

Hong Wang, Chee-Hong Wong, Alice Chin, Ayumu Taguchi, Allen Taylor, Samir Hanash, Sadanori Sekiya, Hidenori Takahashi, Masaki Murase, Shigeki Kajihara, Shinichi Iwamoto, Koichi Tanaka
"Integrated mass spectrometry-based analysis of plasma glycoproteins and their glycan modifications"
Nat. Protoc. 2011, 6 (3) pp 253-269
FIRST Daniel J. Capon, Naoki Kaneko, Takayuki Yoshimori, Takashi Shimada, Florian M. Wurm, Peter K. Hwang, Xiaohe Tong, Staci A. Adams, Graham Simmons, Taka-Aki Sato, Koichi Tanaka
"Flexible antibodies with nonprotein hinges"
Proc. Jpn. Acad., Ser. B 2011, 87, pp 603-616
FIRST Takashi Shimada, Atsuhiko Toyama, Chikage Aoki, Yutaka Aoki, Koichi Tanaka, Taka-Aki Sato
"Direct antigen detection from immunoprecipitated beads using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; a new method for immunobeads-mass spectrometry (iMS) "
Rapid Commun. Mass Spectrom. 2011, 25, pp 3521-3526
FIRST Kaoru Kaneshiro, Yuko Fukuyama, Shinichi Iwamoto, Sadanori Sekiya, Koichi Tanaka
"Highly Sensitive MALDI Analyses of Glycans by a New Aminoquinoline-Labeling Method Using 3-Aminoquinoline/α-Cyano-4-hydroxycinnamic Acid Liquid Matrix"
Anal. Chem. 2011, 83 (10) pp 3663-3667
R. F. El-Kased, C. Koy, P. Lorenz, H. Montgomery, K. Tanaka, H.-J. Thiesen, M. O. Glocker
"A Novel Mass Spectrometric Epitope Mapping Approach without Immobilization of the Antibody"
J. Proteomics Bioinform. 2011, 4 (1) pp 1-9

2010年まで

Helen Montgomery, Koichi Tanaka, Omar Belgacem
"Glycation pattern of peptides condensed with maltose, lactose and glucose determined by ultraviolet matrix-assisted laser desorption/ionization tandem mass spectrometry"
Rapid Commun. Mass Spectrom. 2010, 24 (6) pp 841-848
  田中耕一, 吉野健一, 林雅宏, 内藤康秀, 大久保雅隆
"マトリックス支援レーザー脱離イオン化飛行時間型質量分析計用の検出器"
J. Mass Spectrom. Soc. Jpn. 2010, 58 (3) pp 111-116
Mike Kienbaum, Cornelia Koy, Helen V. Montgomery, Susanne Drynda, Peter Lorenz, Harald Illges, Koichi Tanaka, Joern Kekow, Reinhard Guthke, Hans-Juergen Thiesen, Michael O. Glocker
"MS characterization of apheresis samples from rheumatoid arthritis patients for the improvement of immunoadsorption therapy – a pilot study"
Proteomics Clin. Appl. 2009, 3 pp 797–809
Junko Amano, Daisuke Sugahara, Kenji Osumi, Koichi Tanaka
"Negative-ion MALDI-QIT-TOFMSn for structural determination of fucosylated and sialylated oligosaccharides labeled with a pyrene derivative"
Glycobiology 2009, 19 (6) pp 592–600
田中耕一, 佐藤貴弥, 吉野健一
"遅延引き出し法の基礎"
J. Mass Spectrom. Soc. Jpn. 2009, 57 (1) pp 31-36
田中耕一, 吉野健一, 絹見朋也, 高山光男
"なぜリフレクトロンモードでMS/MS様の測定が可能なのか"
J. Mass Spectrom. Soc. Jpn. 2008, 56 (6) pp 263-268
田中耕一, 吉野健一, 内藤康秀, 豊田岐聡
"なぜリフレクトロンモードやマルチターンによって分解能が向上されるのか"
J. Mass Spectrom. Soc. Jpn. 2008, 56 (2) pp 49-54
Sadanori Sekiya, Tetsuo Iida
"Glycan Analysis by Mass Spectrometry 質量分析による糖鎖解析"
Trends Glycosci. Glycotechnol. 2008, 20 (111) pp 51-65
Yuko Fukuyama, Shuuichi Nakaya, Yuzo Yamazaki, Koichi Tanaka
"Ionic Liquid Matrices Optimized for MALDI-MS of Sulfated/Sialylated/Neutral Oligosaccharides and Glycopeptides"
Anal. Chem. 2008, 80 (6) pp 2171-2179
山田真希, 福山裕子
"MALDI-QIT-TOFMSによるタンパク質糖鎖修飾解析"
島津評論, 2006, 63, pp 67-71
Ei-ichi Matsuo, Chikako Toda, Makoto Watanabe, Noriyuki Ojima, Shunsuke Izumi, Koichi Tanaka, Susumu Tsunasawa, Osamu Nishimura
"Selective detection of 2-nitrobenzenesulfenyl-labeled peptides by matrix-assisted laser desorption/ionization-time of flight mass spectrometry using a novel matrix"
Proteomics 2006, 6, pp 2042-2049
Yuko Fukuyama, Shinichi Iwamoto, Koichi Tanaka
"Rapid sequencing and disulfide mapping of peptides containing disulfide bonds by using 1,5-diaminonaphthalene as a reductive matrix"
J. Mass Spectrom. 2006, 41 (2) pp 191-201
古橋治, 竹下建悟, 小河潔, 岩本慎一, Li Ding, Roger Giles, Sergey Smirnov
"デジタルイオントラップ質量分析装置の開発"
島津評論, 2005, 62, pp 141-151
Sadanori Sekiya, Yoshiki Yamaguchi, Koichi Kato, Koichi Tanaka
"Mechanistic elucidation of the formation of reduced 2-aminopyridine- derivatized oligosaccharides and their application in matrix-assisted laser desorption/ionization mass spectrometry"
Rapid Commun. Mass Spectrom. 2005, 19 (23) pp 3607-3611
Mariana Barboza, Vilma G. Duschak, Yuko Fukuyama, Hiroshi Nonami, Rosa Erra-Balsells, Juan J. Cazzulo, Alicia S. Couto
"Structural analysis of the N-glycans of the major cysteine proteinase of Trypanosoma cruzi. Identification of sulfated high-mannose type oligosaccharides"
FEBS J. 2005, 272, pp 3803-3815
Sadanori Sekiya, Yoshinao Wada, Koichi Tanaka
"Derivatization for Stabilizing Sialic Acids in MALDI-MS"
Anal. Chem. 2005, 77 (15) pp 4962-4968
Noriyuki Ojima, Katsuyoshi Masuda, Koichi Tanaka, Osamu Nishimura
"Analysis of neutral oligosaccharides for structural characterization by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight mass spectrometry"
J. Mass Spectrom. 2005, 40 (3) pp 380–388
Cornelia Koy and Michael O. Glocker, Martin Resch, Koichi Tanaka
"Primary structure details of haptoglobin a chain proteins from human plasma samples are resolved by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight multiple-stage tandem mass spectrometry sequencing"
Eur. J. Mass Spectrom. (Chichester, Eng) 2004, 10 (3) pp 393–399
福山裕子, 和田芳直, 山崎雄三, 尾島典之, 山田真希, 田中耕一
"MALDI-QIT-TOFMSを用いた糖タンパク質の新規構造解析手法:リボヌクレアーゼBへの適用"
J. Mass Spectrom. Soc. Jpn. 2004, 52 (6) pp 328-338
中澤隆, 山口実, 西田希実子, 九山浩樹, 小浜考士, 安藤英治, 岡村高明, 上山憲一, 田中耕一, 乗岡茂巳
"C末端をオキサゾロン経由で活性化したペプチドのアルギニン誘導体化に基づくMALDI‐MSにおける高感度分析"
島津評論, 2004, 61, pp 71-83
岩田庸助, 栗木智子, 戸田千香子, 関谷禎規, Helen Montgomery, 上田輝久, 西村 紀
"ハイスループットスポッティング装置による多次元LC/MALDI‐TOF MSを使ったプロテオミクスオフライン解析法"
島津評論, 2004, 61, pp 49-61
田中耕一, Rachel Martin
"MALDI-QIT-TOF MSnを用いたトップダウンプロテオミクス解析法の試行"
島津評論, 2004, 61, pp 3-10
Koichi Kato, Yoshiki Yamaguchi, Noriko Takahashi, Mamiko Nishimura, Shin-ichi Iwamoto, Sadanori Sekiya, Koichi Tanaka
"Discrimination of Isomeric Fragment Ions Observed in Tandem Mass Spectra of Biantennary Oligosaccharides by Use of Selective Isotope Labeling"
J. Mass Spectrom. Soc. Jpn. 2004, 52 (5) pp 284-288
Sadanori Sekiya, Yoshinao Wada, Koichi Tanaka
"Improvement of the MS/MS Fragment Ion Coverage of Acidic Residue-Containing Peptides by Amidation with 15N-Substituted Amine"
Anal. Chem. 2004, 76 (19) pp 5894-5902
田中耕一, 尾島典行, 山田真希
"広範な翻訳後修飾解析に活用可能なMALDI-QIT-TOF"
蛋白質 核酸 酵素, 2004, 49 (11) pp 1907-1910
Francesco L. Brancia, Helen Montgomery, Koichi Tanaka, Sumio Kumashiro
"Guanidino Labeling Derivatization Strategy for Global Characterization of Peptide Mixtures by Liquid Chromatography Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry"
Anal. Chem. 2004, 76 (10) pp 2748-2755
Takashi Nakazawa, Minoru Yamaguchi, Kimiko Nishida, Hiroki Kuyama, Takashi Obama, Eiji Ando, Taka-aki Okamura, Norikazu Ueyama, Koichi Tanaka, Shigemi Norioka
"Enhanced responses in matrix-assisted laser desorption/ionization mass spectrometry of peptides derivatized with arginine via a C-terminal oxazolone"
Rapid Commun. Mass Spectrom. 2004, 18(7) pp 799-807
鈴木實, 田中耕一, 富永晃生, 御石浩三, 飯田順子, 伊藤恵実, 後藤菜穂子, 鈴木明身
"質量分析によるグライコプロテオミクスⅡ MALDI-QIT質量分析法による糖ペプチドの構造解析"
蛋白質 核酸 酵素, 2003, 48 (8) pp 1194-1199
Cornelia Koy, Stefan Mikkat, Emmanuel Raptakis, Chris Sutton, Martin Resch, Koichi Tanaka, Michael O. Glocker
"Matrix-assisted laser desorption/ionization quadrupole ion trap-time of flight mass spectrometry sequencing resolves structures of unidentified peptides obtained by in-gel tryptic digestion of haptoglobin derivatives from human plasma proteomes"
Proteomics 2003, 3 pp 851–858
Koichi Tanaka
"The Origin of Macromolecule Ionization by Laser Irradiation (Nobel Lecture) "
Angew. Chem. Int. Ed. Engl. 2003, 42, pp 3861-3870
Hiroki Kuyama, Makoto Watanabe, Chikako Toda, Eiji Ando, Koichi Tanaka, Osamu Nishimura
"An approach to quantitative proteome analysis by labeling tryptophan residues"
Rapid Commun. Mass Spectrom. 2003, 17 (14) pp 1642-1650
Hiroki Kuyama, Chikako Toda, Makoto Watanabe, Koichi Tanaka, Osamu Nishimura
"An efficient chemical method for dephosphorylation of phosphopeptides"
Rapid Commun. Mass Spectrom. 2003, 17, pp 1493-1496
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