May 7, 2012: [Materials Provided] Paper on 100 fold improved sensitivity for hydrophobic compounds published.

One of the achievements from last year has been published as a paper in “Analytical Chemistry,” one of the most globally prominent academic journals in the field of analytical chemistry, including mass spectrometry. The results describe how utilizing a newly synthesized compound as an ion adjuvant (matrix) enables measurements of primarily hydrophobic peptides with up to 100 fold improvements in sensitivity over conventional methods.

Yuko Fukuyama1, Ritsuko Tanimura1, Kazuki Maeda2, Makoto Watanabe1, Shin-Ichirou Kawabata1, Shinichi Iwamoto1, Shunsuke Izumi2, Koichi Tanaka1
“Alkylated Dihydroxybenzoic Acid as a MALDI Matrix Additive for Hydrophobic Peptide Analysis”, Analytical Chemistry., 2012, Vol. 84 No.9, pp4237-4243
1 Koichi Tanaka Laboratory of Advanced Science and Technology, Shimadzu Corporation
2 Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University

Presentation materials (Link to overview of the paper published in Analytical Chemistry)