Sep. 11, 2012: [Materials Provided] Paper on a 10,000 fold increase in phosphopeptide sensitivity published.

 A paper has been published in “Rapid Communications in Mass Spectrometry,” a prominent academic journal that posts breaking news regarding the latest technologies in the field of mass spectrometry. This paper describes the achievement of up to 10,000 times the sensitivity of conventional methods with respect to phosphorylation, one of the most important modifications after protein translation.

Yuko Fukuyama, Kohei Takeyama, Shin-ichirou Kawabata, Shinichi Iwamoto, Koichi Tanaka
“An optimized matrix-assisted laser desorption/ionization sample preparation using a liquid matrix, 3-aminoquinoline/α-cyano-4-hydroxycinnamic acid, for phosphopeptides”, Rapid Commun. Mass Spectrom. 2012, 26, pp2454-2460
Koichi Tanaka Laboratory of Advanced Science and Technology, Shimadzu Corporation

Presentation materials(Link to overview of the paper published in Rapid Communications in Mass Spectrometry)